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Nkarta Stock Surges on Positive Preliminary Data from Natural Killer Cell Programs

2022.04.25 18:22

Nkarta Stock Surges on Positive Preliminary Data from Natural Killer Cell Programs

By Sam Boughedda

Investing.com — Biopharmaceutical company Nkarta Inc (NASDAQ:NKTX) surged Monday after it reported positive preliminary Phase 1 data from independent dose-finding studies.

The studies were for its two lead chimeric [with cells with different genes] antigen receptor natural killer cell therapy candidates, NKX101 and NKX019.

The company said for NKX101, three out of five patients with relapsed or refractory acute myeloid leukemia (AML) treated with a three-dose regimen achieved a complete response with full hematologic recovery.

Meanwhile, for NKX019, five out of six patients with relapsed or refractory non-Hodgkin’s lymphoma (NHL) treated with a three-dose regimen achieved a response, and three out of six achieved a complete response.

“We’re excited to see our CAR NK co-lead candidates, NKX101 and NKX019, show such striking early single-agent activity in heavily pretreated patient populations, with an exceptional safety profile without the side effects associated with CAR T cell therapies,” said Paul Hastings, President, and CEO of Nkarta. 

“These encouraging data across multiple indications further validate Nkarta’s best-in-class NK cell platform, as we seek to transform cancer treatment,” Hastings added.

Nkarta stock is currently up 93%.

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