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Earnings call: MaxCyte sees steady growth and strategic partnerships in Q1 2024

2024.05.11 16:41

Earnings call: MaxCyte sees steady growth and strategic partnerships in Q1 2024

MaxCyte, Inc. (MXCT) reported a solid start to the fiscal year 2024, with total revenue reaching $11.3 million in the first quarter. The company’s financial health appears robust, with a combined total of $202.5 million in cash, cash equivalents, and investments, and no debt reported at the end of Q1. MaxCyte’s earnings call highlighted their strategic growth through new SPL agreements, a disciplined approach to potential acquisitions, and a focus on supporting cell therapy developers.

Key Takeaways

  • Total Q1 revenue of $11.3 million, with core revenue at $8.2 million.
  • SPL program-related revenue contributed $3.2 million, bolstered by a regulatory milestone.
  • Four new SPLs signed in 2024, including one with Be Biopharma.
  • Financial outlook for 2024: flat to 5% growth in core revenue, around $5 million from SPL revenue, and over $175 million in cash and investments by year-end.
  • No debt on the balance sheet.
  • Long-term growth strategies include further investments in product development and field application scientists.
  • The company is evaluating potential acquisitions and remains selective in pursuing strategic partnerships.

Company Outlook

  • MaxCyte reaffirms its 2024 revenue outlook, with expectations of flat to 5% growth in core revenue.
  • SPL program-related revenue is anticipated to be approximately $5 million for the full year.
  • The company projects to finish 2024 with a minimum of $175 million in cash and investments, maintaining a debt-free status.

Bearish Highlights

  • Drug discovery revenue remained flat, showing no growth from the previous year.

Bullish Highlights

  • Cell therapy revenue and PA revenue both showed growth, with PA revenue exceeding expectations.
  • The company is optimistic about the market outlook for cell therapy developers.
  • MaxCyte’s proactive approach to partnerships and acquisitions aims to accelerate the development and delivery of therapies.
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Misses

  • The company did not provide specifics on the surprise pivotal trial mentioned during the call.

Q&A Highlights

  • MaxCyte is focusing on forming SPLs with smaller to mid-sized biotechs rather than large pharmaceutical companies.
  • The company is seeing diversity in cell types and molecules used by their partners.
  • MaxCyte emphasized discipline in evaluating potential deals, avoiding undervalued opportunities or those not aligning with their strategic goals.

MaxCyte’s first quarter of 2024 sets a positive tone for the year, showcasing the company’s strategic acumen and financial stability. With the cell therapy market evolving, MaxCyte is positioning itself as a key player by expanding its SPL portfolio and staying flexible in its partnerships. The company’s commitment to growth, both through internal development and potential acquisitions, underscores its readiness to meet the challenges of a complex and competitive landscape. As MaxCyte continues to support groundbreaking cell therapy developments, investors and industry watchers will be keenly awaiting the next earnings call for updates on the company’s progress and strategic moves.

InvestingPro Insights

MaxCyte, Inc. (MXCT) has demonstrated a strong financial posture with a noteworthy liquidity position, as evidenced by their cash reserves surpassing their debt obligations. The company’s gross profit margins stand out, reflecting a robust business model with efficient cost management. However, it’s important to note that analysts have tempered their earnings expectations for the upcoming period, suggesting that investors should keep a close watch on future financial disclosures for any signs of pressure on profitability.

InvestingPro Data metrics reveal a mixed picture. The company’s market capitalization is currently at $484.48 million, with a negative P/E ratio of -13.31, indicating that investors are expecting future growth to justify the current valuation. Moreover, the gross profit margin for the last twelve months as of Q1 2024 is an impressive 88.32%, highlighting the company’s ability to maintain high profitability on its sales. The revenue growth of 6.8% over the last twelve months also suggests a steady upward trajectory, albeit analysts anticipate a sales decline in the current year.

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InvestingPro Tips for MaxCyte include the significant return over the last week, with a price total return of 25.73%, and a large price uptick over the last six months, at 44.07%. These movements in the stock price may indicate market optimism about the company’s strategic initiatives or a reaction to broader market trends.

For investors seeking more in-depth analysis and additional insights, there are 11 more InvestingPro Tips available for MaxCyte at To access these valuable tips and enhance your investment strategy, use coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription.

Full transcript – MaxCyte NAQ (MXCT) Q1 2024:

Operator: Good day, and thank you for standing by. Welcome to the MaxCyte First Quarter 2024 Earnings Conference Call. At this time all participants are in a listen-only mode. After the speakers presentation there will be a question-and-answer session. [Operator Instructions] Please be advised that today’s conference is being recorded. I would now like to hand the conference over to your speaker today, Erik Abdow, Investor Relations. Please go ahead.

Erik Abdow: Good afternoon, everyone. Thank you for participating in today’s conference call. On the call from MaxCyte, we have Maher Masoud, President and Chief Executive Officer; and Douglas Swirsky, Chief Financial Officer. Earlier today, MaxCyte released financial results for the first quarter ended March 31, 2024. A copy of the press release is available on the company’s website. Before we begin, I need to read the following statement. Statements or comments made during this call may be forward-looking statements within the meaning of federal securities laws. Any statements contained in this call that relate to expectations or predictions of future events, results or performance are forward-looking statements. Actual results may differ materially from those expressed or implied in any forward-looking statements due to a variety of factors, which are discussed in detail on our SEC filings. The company has no obligation to publicly update any forward-looking statements, whether because of new information, future events or otherwise. And with that, I will turn the call over to Maher.

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Maher Masoud: Thank you, Erik. Good afternoon, everyone, and thank you for joining MaxCyte’s first quarter 2024 earnings call. MaxCyte reported $11.3 million of total revenue in the first quarter, including core revenue of $8.2 million and $3.2 million of SPL program-related revenue. We were pleased with the results in our core business, which delivered in line with our plan, along with SPL program-related revenue, which came in above our expectations. We are also thrilled with our progress in signing new SPLs with 4 already signed 2024, including Be Biopharma most recently. Following the first quarter, we remain on track in our financial projections for the year and are confident in the trajectory of the overall business. The operating environment for our customers remained largely unchanged from our last earnings call. We believe the funding environment has improved as evidenced by the capital markets activity during the first quarter. We have seen several existing and prospective SPL partners raise capital in recent months. Over the past couple of years, we saw cell therapy companies prioritize their lead programs and deprioritize other programs, resulting in variable levels of demand for our instruments and PAs in 2023. Though there are fewer new cell therapy programs throughout the industry today due to program reprioritization, we believe this has resulted in an industry focus on assets that are further along in their development or have a higher probability of making it to the clinic. Additionally, MaxCyte’s late stage preclinical and early stage clinical customers, who have reevaluated their programs over the past couple of years, continue to utilize our platform for their lead programs. We are becoming increasingly optimistic on the market outlook for cell therapy developers and continue to assess industry demand levels based on direct conversations with our existing and prospective customers. The time frame for when a customer secures funding to when they make research and clinical spending decisions can take time. And our business is not directly correlated with the level of funding in any given quarter. General trends in the non-viral cell therapy market continue to bode well for the use of our ExPERT platform. Companies continue to pursue more complex cell therapies across a variety of different indications with multiple engineering steps, which MaxCyte’s electroporation technology is well equipped to deliver. Looking specifically at the quarter, the core business performed as expected across cell therapy and drug discovery. We saw a return to growth in our cell therapy business compared to last year’s first quarter, and we were relatively flat in drug discovery revenue compared to last year. Doug will cover that in more detail, but I will point out that our installed base of instruments expense of 708 as of March 31, 2024. We executed well against our pipeline of instrument opportunities in the first quarter and our position as planned for the remainder of the year. On PAs, revenue is up from the comparable prior year period and improved sequentially from the fourth quarter of 2023. The PA growth that we experienced was reflective of broad-based demand across the customer base, and we were very encouraged to see an uptick in our PA revenue compared to 2023. PA sales are always dependent upon the activity level of customers, stage of development programs and desired inventory levels at customers, all of which can result in demand that can be lumpy from one quarter to another. Turning to our SPLs, we recognized $3.2 million of SPL program-related revenue in the first quarter of 2024. This included a regulatory pivotal milestone that we did not originally forecast for 2024. We have raised our guidance for the SPL program-related revenue line to account for this milestone, which Doug will address in more detail. Accomplishment of the previously non-forecasted regulatory pivotal milestone underlies the strength of our business model. As our therapeutic development customers move further into the clinic, we are positioned to receive revenue from milestone achievements on occasion, sooner than anticipated. So far in 2024, we have signed 4 SPLs, including Be Biopharma Wugen, Imugene, and Lion TCR. Our most recently signed SPL that we announced in April, Be Biopharma, is developing a proprietary class of engineered B cell medicines, BCMs, designed to produce therapeutic proteins specific to a certain disease. MaxCyte’s platform will support the development of Be Bio’s BCM programs to address unmet needs of patients with genetic diseases, cancer and more. The addition of Be Biopharma brings the total number of SPLs in our portfolio to 27, which further showcases our position as the partner of choice with technology capability across multiple cell types to cell and gene innovators. Moreover, we remain excited about the commercial opportunity of CASGEVY. CASGEVY has been approved for certain indications in the United States, Great Britain, European Union, Saudi Arabia and Bahrain, with a new drug submission that has been accepted for priority review by Health Canada. As a reminder and as stated on our last earnings call, MaxCyte will only recognize revenue once the patient has been infused, which can take a number of months from the time a patient enrolls in the therapy program. We do not have sufficient visibility into the timing of patient dosing, and therefore, continue to exclude any CASGEVY-related commercial milestone revenue in our updated 2024 outlook for SPL program-related revenue. We will provide updates on CASGEVY as they come from Vertex (NASDAQ:). The current and prospective client relationships that we have built and fostered are truly unique and reflective of our platform’s value proposition. At MaxCyte, we pride ourselves not only on our proven electroporation technology, but on differentiated support that we provide to our customers. We are present throughout the entirety of our customers’ programs once they begin utilizing our platform. Our support system includes scientific customer service from our 36-plus trained field sales and application scientists to provide customer research and development support. As part of our SPL relationships, clients have access to our FDA drug master file, which can help with regulatory understanding of the manufacturing process required for approval and help derisk one part of the manufacturing process for our SPL customers. That’s our platform and service that we offer to our clients is truly an all-encompassing end-to-end solution. We believe our value proposition has resonated well with existing customers and will drive substantial opportunity for MaxCyte over the long term. This quarter and over the course of 2024, we continue to deliberately evaluate and improve our business. We are focused on investing in our business to drive growth and to best support the programs of our current and future clients. Notably, we have invested in additional customer support for our SPL clients and are working towards ensuring we are working with customers early in the development and providing them with the best know-how application in the process. In summary, we are very pleased with our first quarter results and believe that we remain in a strong position to deliver our 2024 plan. As the cell therapy industry continues to move towards non-viral cell engineering approaches, I am very optimistic about the opportunity for MaxCyte both in the near term and long term as the premier cell engineering platform. With that, I will now turn the call over to Doug to discuss our financial results. Doug?

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Douglas Swirsky: Thanks, Maher. Total revenue in the first quarter of 2024 was $11.3 million compared to $8.6 million in the first quarter of 2023, representing an increase of 32%. We reported core revenue of $8.2 million compared to $7.8 million in the comparable prior year quarter, representing an increase of 5%. This includes revenue from cell therapy customers of $6.4 million, which increased 7% year-over-year, and revenue from drug discovery customers of $1.8 million, relatively flat year-over-year. Within core revenue, instrument revenue was $1.9 million compared to $2.2 million in the first quarter of 2023. Lease revenue was $2.6 million compared to $2.8 million in the first quarter of 2023, and processing assembly, or PA revenue, was $3.4 million compared to $2.6 million in the first quarter of 2023. We are pleased with the strong performance of PAs, which was a little better than planned, which we will continue to monitor as we move through the course of the year. Please note, we have added an appendix slide to our corporate presentation with the new quarterly historical disclosure for these new metrics. We recognized $3.2 million of SPL program-related revenue in the first quarter of 2024 compared to $0.8 million of SPL program-related revenue in the first quarter of 2023. We exceeded our initial milestone expectations for the first quarter, driven by a regulatory pivotal milestone that we had not forecasted or anticipated in 2024 due to a positive timing development at one of our SPL customers. Moving down the P&L. Gross margin was 88% in the first quarter of 2024, which was comparable to 88% in the first quarter of the prior year. Our margins came in lower than our historical levels over the past year when excluding SPL program-related revenue due to fixed overhead cost absorption. We believe that as we move closer towards previous revenue levels, margins should improve. Total operating expenses for the first quarter of 2024 were $22.2 million compared to $20.8 million in the first quarter of 2023. The overall increase in operating expenses was primarily driven by growth in sales and marketing expenses, as well as R&D expenses, with specific investments in product development and application know-how. Going forward, the company continues to be disciplined, making moderated and targeted investments to drive long-term growth, including an innovative product development and field application scientist and additional technological capabilities. We finished the first quarter with combined total cash, cash equivalents and investments of $202.5 million and no debt. Moving to our full year 2024 guidance, we are reiterating our core revenue outlook and raising our initial SPL program-related revenue guidance. Core revenue is expected to be flat to 5% growth compared to 2023. As Maher discussed, our guidance assumes an operating environment for our customers that has remained largely unchanged from our prior earnings call. We now expect SPL program-related revenue to be approximately $5 million in 2024. The increase in our SPL program-related revenue outlook is a result of the unexpected regulatory pivotal milestone we achieved in the first quarter, which was previously not incorporated in our 2024 guidance. As a reminder, our 2024 outlook also does not include royalty revenue on CASGEVY. Finally, MaxCyte has maintained a strong financial position and continues to expect to end 2024 with at least $175 million in cash, cash equivalents and investments and no debt on our balance sheet. I would like to close by reiterating that we remain well positioned to execute on our 2024 revenue outlook and remain laser focused on managing our spend and balance sheet to deliver long-term growth. Now I’ll turn the call back over to Maher.

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Maher Masoud: Thank you, Doug. Overall, we are very excited by our progress so far in 2024. We look forward to supporting our customers in their development stages as they progress through the clinic and remain committed to further expanding our SPL portfolio. We believe that we continue to be the premier enabler of non-viral cell therapies and would like to thank our MaxCyte team for their continued hard work. With that, I will turn the call back over to the operator for the Q&A. Operator?

Operator: Thank you. [Operator Instructions] Our first question comes from the line of Dan Arias with Stifel. Your line is now open.

Daniel Arias: Good afternoon, guys. Thanks for the questions. Maher, maybe just to talk about some of the components of the revenue bolus for the quarter. PA revenues up sequentially, to your point. And so when we think about the rest of the year — and I hear you on your comments about there being lumpiness there. But it also seems like what you record there on the PA side is largely a function of activity and just project intensity, which I think you alluded to as well. And so, it feels like the funding environment is trending in the right direction. Is there a reason why PA revenues wouldn’t continue to just push higher here across the year now that you’re out of what is the choppiest quarter of the four?

Maher Masoud: Yes. Absolutely, Dan. So obviously — thank you for the question. Obviously, we’re still holding steady in terms of our guidance for the year. We’re still cautiously optimistic in terms of the rest of the year. We were not pleasantly surprised. This is what we expected coming out of last year. This is — the end of last year, we saw some stabilization. We’re seeing it continue through the year. And it’s a mix. It’s broad-based. It’s not just related to necessarily one particular customer when we see that increase. It’s across the customer base we’re seeing it. But we’re not ready just yet to in any way increase revenues throughout the year. We’re still seeing how the year plays out. But we’re cautiously optimistic. Doug, anything else to add there?

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Douglas Swirsky: No. I mean we’re — I think we’re pleased with how PAs were this quarter, but I think it’s too soon to tell whether some of that’s timing or whether we’re going to have significantly higher PA revenue than we were expecting and what we projected out the year. So we’re holding our guidance at the levels we provided on the March call for revenue.

Daniel Arias: Yes. Okay. Makes perfect sense. And then maybe just higher level, Maher, can you just talk to the tone from customers that you’re hearing right now? I mean it does feel like there’s a little bit of a sigh of release there, just given where financing activities have gone over the last couple of months. So to your point on project prioritizations, are you starting to see things open up a little bit that maybe felt like they were less likely to be worked on a couple of months ago or six to 12 months ago? And can you just maybe talk about confidence that the industry is seeing what it needs in order to keep heading in this direction in terms of increased activity, preclinical and commercial?

Maher Masoud: Yes. I think you hit it on the head there is that we are seeing the activity start to come back. The confidence is coming back. I think that’s evident slightly from we signed four SPLs to start the year, but also if you look at the capital markets, a few of our partners have very significant amount of money in the capital markets in Q1. And we’re seeing that confidence come back in the market. We think it’s the early stages of that. We’re going to keep our eye on it to make sure that it’s not just a small little bump. But I think working with our customers, even though they’re still rationalizing what programs are taking into the clinic and how many programs they take into the clinic, we feel fairly confident that we’re cautiously optimistic, as we keep saying. But the quarter is kind of a prognosticator of where we are and where the market is right now and how it seems to be coming back slowly.

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Daniel Arias: Okay. If I could just sneak one more nuance on to that last point. When you obviously — well, maybe not obviously, but I assume you’re looking at who’s raising money and who’s not raising money. Is it fair to say that those that have maybe not had a public raise are showing signs of improvement as well? Or does the line really get drawn down the middle where you have some that have financed and therefore are in a better position? And those are the companies that are starting to open up the spigot a little bit. Those that haven’t done that haven’t really changed. Is that the dynamic? Thank you.

Maher Masoud: I think first off, on PAs, I think you don’t need to see the things snap back to strong levels for folks to start making investments and moving their programs forward. I think where the timing of capital raise is going to impact things may be on when an instrument purchase takes place. So I think those capital acquisitions are going to be more tied to the fundraising than certainly the PA utilization is going to be.

Daniel Arias: Okay. Very good. Thank you.

Maher Masoud: Thank you, Dan.

Operator: Thank you. Our next question comes from the line of Matt Larew with William Blair. Your line is now open.

Matt Larew: Good afternoon. Just maybe following up on that last point, acknowledging that it takes some time for flow through from perhaps a successful capital raise to release of that into a budget. On the instrument side, what are you starting to hear about from customers on a budget perspective? What does the, perhaps the instrument pipeline look like relative to maybe the end of last year just because, obviously, while PAs were strong, instrument’s still a little bit softer in the quarter.

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Maher Masoud: Yes. Matt, let me answer that, and then I’ll let Doug also weigh in. So what we’re seeing in terms of the instrument side really is the prognosticator for that is what we’re seeing on the PA side. That’s usually where you start to see the recoveries normally in PAs because the CapEx spend is far less than we do for instrument side — for an instrument purchase. So we’re hopeful and we’re optimistic that what we’re seeing on the PAs will lead later in the year to potentially where now customers are willing to make purchases that maybe last year that were not willing to make. But again, it’s just that leading indicators because of the PAs. I’m not so sure we want to at this point indicate that it’s going to lead to future instrument sales just because the PAs have increased. Doug, anything else to add there?

Douglas Swirsky: I mean it’s a good question, and I think it’s a good opportunity to remind everybody what makes up core revenue. There’s the leases, which I think we’ve got good visibility in. It’s very stable. We saw some growth there. And then there’s the PAs, which are a lot tougher to project. And then instrument sales. Instrument sales really is a — we build up our forecast based on very detailed information that comes from the commercial team on each opportunity that they’re looking at. And so when we think about the year, certainly instrument revenue wasn’t as strong as PAs was this quarter, but we still feel very good about the guidance we provided when we’re looking specifically at the book of business that they’re working through now on the instrument sales side.

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Matt Larew: Okay. Understood. Maher, you referenced in the prepared remarks, I think adding additional SPL support for clients and starting to work with them earlier. I’m curious if this is sort of a step function change or new for you, or if there are particular services or capabilities that you’re adding in terms of how you interact with clients that are different from before? And whether this is something that’s sort of been an ask from clients or more of a push from you either from a competitive or a servicing standpoint.

Maher Masoud: Yes, absolutely. Great question. Actually, it’s more of a push from internal rather than being asked from clients, per se. We’ve always — if you look at what we do, we do a complete end-to-end solution. We provide support to our customers where from the time they first work with us all the way through the clinic, we want to make sure, I think I said on the last call as well, that we’re doubling down that support. So we’re staying ahead of the competition, and we’re providing support now with better communication, both electronic communication as well as face-to-face communication. So we’re building out systems to ensure that the support that we provide to our SPL partners, whether it’s regulatory or quality or any potential issues that they have while they’re in their clinical development, even potential commercial development, we stay ahead of it, and the turnaround time is even faster than before. So we’re ensuring that we’ve done in the past, we’re doing even more so of it and really coming of age with where the industry is going and where we want to make sure as these therapies need to make it to the clinic faster and make it to patients faster, that we derisk that step where they’re working with us. So we’re investing extra resources and really capabilities in that area to make sure we stay ahead of the competition and keep up and align our interests with our partners.

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Matt Larew: All right. Thank you.

Operator: Thank you. Our next question comes from the line of Jacob Johnson with Stephens. Your line is now open.

Jacob Johnson: Hi, thanks. Good afternoon and congrats on the quarter. You guys called out kind of a pivotal trial surprise in the quarter. I’m just curious if this relates to a new or an existing therapy. I think program revenues don’t include CASGEVY, so I’m curious if it’s a new customer. And maybe I’ll dovetail that into looking at your chart on potential commercial approvals, it looks like you’re not really expecting anything until 2026. I’m just curious if this kind of surprise pivotal changes your thinking about that. Thank you.

Maher Masoud: Yes. Jacob, thanks for that. I’ll take that. It doesn’t quite change our thinking on that. Obviously, we can’t comment in terms of what customer it is or why it happened sooner than it should be for confidentiality reasons with our partners. However, as I mentioned, it does speak to our business model in the sense of there are going to be times where some of our current partners that have signed licenses with us are going to reach milestones sooner than they even anticipated or that we anticipated, and we’ll get the benefit of that. And that’s what happened here. I wouldn’t change the 2026 or 2027 time line for next generating events for us. We’re still — that’s what you see, that we’re confident with that. But this is a positive. This speaks to exactly why we have these licenses, why we provide the support, and what I’ve mentioned in the past, which is these are not like antibody therapies. There’s a higher potential that you’re going to have potential clinical efficacy earlier than anticipated by our partners, which will benefit us and benefit patients and our partners as well. Does that answer your question, Jacob?

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Jacob Johnson: Yes. Yes, that’s helpful. Thanks, Maher. And maybe Dan asked you about customers spending money, received funding versus maybe those who hadn’t. I’m just curious, maybe looking, dicing it a different way. Just curious if there’s any difference in PA demand, if it’s maybe more skewed to customers in the clinic, or if you did have some maybe preclinical or earlier — demand from preclinical or earlier stage customers as well?

Maher Masoud: Yes. I’ll answer that, and if Doug wants to weigh in. I think it’s spread across. It’s not just clinical. It’s clinical and preclinical demand as well as research. We’re seeing that across the board, which is what we want to see. We want to see the healthy business both for the SPLs and the non-SPL customers. And that’s what we saw sequentially from this quarter to last quarter. So it’s a healthy demand across the board, Jacob.

Jacob Johnson: Got it. Thanks for taking the questions guys.

Maher Masoud: Thank you, Jacob.

Operator: Thank you. Our next question comes from the line of Matt Hewitt with Craig-Hallum Capital Group. Your line is now open.

Unidentified Analyst: Hi, guys. This is Jack on for Matt. Congrats on a good readout. We just have one question. So after like a four year of new SPL agreements at the start of the year, could you just give us an update on that pipeline and whether you expect additional agreements this year? Thanks.

Maher Masoud: Thanks, Jack. I can speak to that. And then, Doug, feel free to speak to that as well. Obviously, a very healthy start to the year. We’re still — what we’ve mentioned in the past, we’re comfortable with the three to five per year. The funnel and the pipeline itself for future SPLs is healthy. We’re confident that we can continue to have those three to five. I won’t comment on whether we’re going to sign another one this year just yet. Obviously, for obvious reasons, as I mentioned last time, sometimes you see a bolus of SPLs signed to any particular time. The reason being is we’re oftentimes working in research, working with these customers, really in the benches with them, supporting them. And then from there, it ends up being a negotiation a little bit thereafter where now we’re negotiating licenses where they’re about to enter into the clinic. So sometimes you might have it where you have three to four at the same time, we’ve been working with in the past 12 months, 18 months that are about to sign licenses. So that’s why you see a bolus. But we’re completely confident at three to five moving forward. Won’t speculate as to whether we’ll sign another one. And then the funnel itself is healthy, and that’s why we’re confident at three to five moving forward as well. Jack, did that answer your question?

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Unidentified Analyst: Yes, that’s helpful. Thank you.

Operator: Thank you. Our next question comes from the line of Mark Massaro with BTIG. Your line is now open.

Unidentified Analyst: This is [Jinny] (ph) on for Mark. Thanks for taking the questions. So just a quick one on VLx adoption. It sounds like that might be more of a lagging indicator relative to PAs. But just any new appetite or early feedback to report there?

Maher Masoud: Yes. Thanks for the question. On the VLx in terms of — as I mentioned last time, we’re still working with early adopters. We’re taking a step back to ensure that we do this where we understand the true application needs for the VLx. I won’t mention for confidentiality reasons the name of those early adopters, but it’s just to ensure that we understand the space that we’re entering into, where it’s different than cell therapy, where we’re really trying to disrupt the industry here. And not just with from the VLx, but just in terms of production of proteins in a transient manner that is at a scale that’s never been done before. So in terms of the PA usage for that, we haven’t disclosed that. In terms of instrument sales, we haven’t disclosed that. But we’re still working with early adopters to truly understand the space and then launch in a manner that allows us to have true market adoption for the VLx and applications around the VLx as well. But we have not disclosed anything specifically there.

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Unidentified Analyst: Perfect. Understood. And then just my follow-up. You guys had a pretty healthy balance sheet. Just any tuck-in acquisitions or tech that you might look to evaluate, particularly for upstream or downstream steps, kind of like cell enrichment or harvesting? Just any conversations going on there? Thanks.

Maher Masoud: We have an active corporate development effort. Clearly, we’re not in a position to talk about specific targets we’re looking at. I think the types of things you mentioned are sort of in the realm of opportunities we would look at. But we’ve got healthy effort just to balance out our initiatives to target both inorganic and organic growth opportunities. So this is one of the use of proceeds when we went public, so we’re mindful that. That’s part of the reason why we have the healthy balance sheet that we do. And our goal is to look closely at things but be very prudent. And I think it’s healthy that we’re evaluating things. It’s also very good that we’ve been very disciplined in not pulling the trigger on things that either we didn’t think were valued correctly or just weren’t the right fit.

Unidentified Analyst: Awesome. Thanks for taking all the question.

Maher Masoud: Thank you.

Douglas Swirsky: Thank you.

Operator: Thank you. Our next question comes from the line of Jacqueline Kisa with TD Cowen. Your line is now open.

Jacqueline Kisa: This is Jacqueline Kisa on for Steven Mah. Thanks for taking the questions. Just to start off, with regards to your new and ongoing BD discussions for new SPLs, are you seeing these discussions weighted more towards emerging biotechs or large pharma? Is there like a noticeable mix or anything?

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Maher Masoud: Yes. Hi, Jacqueline. Thank you for the question. I’ll take that. It’s more towards — it’s not large pharma. It’s more towards, I’d say, smaller to mid-sized biotechs, and it’s a mix of what we’re seeing there. Obviously, as the industry keeps changing and evolving and as cell therapies have greater adoption, we could see that mix begin to change as well. Whether it’s from early to mid-size to larger biotechs, it’s a good mix. I mean it’s a good question. I think you’re seeing it across the board. When I say large pharma, we don’t have — that’s not our focus right now. It’s more on the support that’s needed for that smaller to mid to even larger-sized biotechs.

Jacqueline Kisa: Right. Great. Thank you. And then if you look across the clinical programs you’re supporting, can you speak to the diversity of the cell types and molecules that your partners are using to create their cell-based therapies? And has this trended over the past 12 months? And if you’re willing to call any emerging trends with regards to that, that would be really cool, too.

Maher Masoud: Yes. Absolutely, Jacqueline. So actually, that’s the beauty of our support and what we do truly best is it’s emerging across cell therapies. Whether it’s T cells or NK cells, whether it’s TILs or TCRs, we’re working with all of them. And obviously for the indications, it’s increasing where you went from blood cancers to solid tumors, which is where we’re having a presence in. And then you’re seeing the space really get more complex with the companies we’re working with and truly begin to go into other indications. You’re seeing autoimmune diseases begin to really take shape here, and that’s where it seems the space is lending itself. And we’re working with a few of our partners on immune disorders, cell therapies for autoimmune diseases, rare diseases. So it’s an entire breadth, and that’s what we anticipate. We anticipate the field continue to evolve, continue to mature and really get more complex. And that’s what we’ve built the last 15, 20 years to ensure that we’re ahead of competition and working with everyone with regards to the cell type, regardless of the modality and indication. So, I hope that answers your question, Jacqueline.

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Jacqueline Kisa: That’s great. Thank you so much. I appreciate it.

Operator: Thank you. And I’m currently showing no further questions at this time. I’d like to hand the call back over to Maher Masoud for closing remarks.

Maher Masoud: Yes. Thank you, operator, and thank you all for joining today’s call. I look forward and we look forward to speaking with all of you again on our next earnings call in a few months. Thank you.

Operator: This concludes today’s conference call. Thank you for your participation. You may now disconnect.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.



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